On a daily basis, trust & safety teams maintain platform integrity, just as non-profits tackle on-the-ground exploitations and academics pursue innovative research. Niche expertise and disjointed efforts by distinct groups cannot adequately craft safety in an increasingly seamless world. Cross-sectoral solutions are a need of the hour, not merely an adjunct, to truly mitigate the tangible consequences of complex harms (e.g., disinformation, synthetic content, algorithmic biases). Such synergy deepens platform trust and retention while bolstering civil society and non-profit impact. This panel will explore the opportunities and barriers for routinizing cross-sectoral exchange specifically in areas of child safety, health information, and social technology. Panelists will share pointers and approaches for consistently synchronizing information sharing, technical and analytical expertise, capacity building, reporting mechanisms, and outreach programs across spheres focused. The discussion will offer realistic recommendations to sew collaborative practices bridging knowledge generation, community service, and safety work.